|
KMID : 0882420150890060690
|
|
Korean Journal of Medicine
2015 Volume.89 No. 6 p.690 ~ p.694
|
|
|
IgG4-related Disease Controlled by a Low-dose Steroid and Mycophenolic Acid
|
|
Kim Ji-Eun
Cha Jin-Joo
Ko Gang-Jee
Kwon Young-Joo
Kim Sun-Woo
Hong Yu-Ah
|
|
|
Abstract
|
|
|
|
IgG4-related disease (IgG4-RD) is a group of fibro-inflammatory diseases affecting multiple organ systems, pathologically characterized by tissue infiltration with abundant IgG4-positive cells. We here report a case of IgG4-RD that was successfully controlled by mycophenolic acid (MPA). A 62-year-old male visited complaining of dizziness and loss of appetite. He had a clinical history of autoimmune pancreatitis treated with steroids and cyclophosphamide 5 years prior, and had also been diagnosed with Hashimoto’s thyroiditis at the age of 55 years. We initially prescribed prednisolone (1 mg/kg), tapered to 5 mg/day over 8 months. However, his eosinophilia gradually deteriorated, and we added cyclophosphamide (1 mg/kg daily) for the next 7 months. His laboratory data fluctuated when he was on low-dose predinisolone and cyclophosphamide, and we thus changed his medication to prednisolone combined with MPA for the following 63 months. Currently, his laboratory findings are stable.
|
|
|
KEYWORD
|
|
|
IgG4, Mycophenolic acid, MPA, Eosinophilia
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|